Do you use a comprehensive volumetric, rather than numeric, cutoff in consideration of SRS vs WBRT for brain metastases?
If a patient has a limited number of brain metastases (e.g., <3 total) but the additive volume of these intracranial metastases is high (e.g., each lesion is 100 cc to 125 cc, such that the total volume is ~400 cc), do you selectively employ WBRT versus SRS?
If so, what is the total volume of intracranial metastatic disease that serves as a cutoff between SRS vs. WBRT approaches to palliation?
1 Answer
Mednet MemberInvited Expert
Radiation Oncology · University of New Mexico School of Medicine
Answered on
I think there is quite a bit to unpack from this question.
First, I would contend that there is a whole world between SRS & WBRT. There are even active multi-institutional randomized studies being performed to better define this world. Many institutions, including mine, have largely shifted away fro...
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