Do your radiation treatment recommendations change if a breast cancer patient does not complete a full course of neoadjuvant chemotherapy?

No. For the usual patient who has operable/resectable breast cancer, who is planned to have induction chemo followed by surgery, failure to complete the induction chemo would not alter my planned RT. Inherent to this question is the related question of: "Should we alter the RT plans based on the res...

Agree with Dr. @Dr. First Last. We continue to base radiation dose/volume/design currently on pre-chemotherapy staging (including PET, axillary imaging, and often MRI) regardless of completion of NaC. There is clearly an interest in the de-escalation of RT, which ongoing trials will help address. HE...