Does anyone utilize P2Y12 assays to determine if clopidogrel may be ineffective when used for DAPT?
If yes, if the assay shows they are a non-responder, do you switch to ticagrelor?
Answer from: at Academic Institution
Yes, if the patient has undergone genetic testing indicating nonresponsiveness to clopidogrel, I would consider substituting ticagrelor. In most cases, DAPT is short-term, typically lasting for one month, after which aspirin monotherapy would be sufficient.
I do check the P2Y12 assay in patients experiencing stroke on clopidogrel, especially before asking neurosurgery to see for "failed best medical therapy " in ICAD.
Comments
at University of Colorado, Climate & Health Dept If someone has a clinical or radiographic progress...
Yes. I do, especially with another ischemic event in those on Plavix monotherapy (for small or large vessel disease) or DAPT (even for a short period with an event recurring due to atherosclerotic disease or small vessel disease) during that time of DAPT therapy. Also, if genetic testing is done, I ...