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Does Oncotype score affect your decision to do regional nodal irradiation in a patient with early-stage breast cancer?

If a patient with early-stage breast cancer s/p lumpectomy is noted to have 1/3 SLNs positive for ITCs (and no other negative prognostic factors) would Oncotype Dx score impact your decision to offer regional nodal irradiation in additional to whole-breast RT?
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What would you recommend for early-stage breast cancer s/p lumpectomy with 1/3 SLNs + for ITCs (and no other negative prognostic factors)?

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1 Answer
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Radiation Oncology · Varian Medical Systems/Allegheny health network
Answered on · Updated on

For ITC, would not change based on genomic testing and treat like node negative disease.

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