Does pathologic complete response impact your selection criteria for tumor bed boost of breast cancer patients' status post neoadjuvant chemotherapy and breast-conserving surgery?

I have not used response, including pathologic complete response, as a reason to change my criteria for tumor bed boost following neoadjuvant chemotherapy. I typically will boost patients that meet at least one of the following criteria: age <50, ER-, cT3, grade 3, LVSI.