While additional APLAs such as aPS/PT are being investigated for clinical relevance, to date, they are not established markers for disease. I would interpret the aforementioned paper with caution, as these antibodies were tested in individuals with known and diagnosed APS. Their role in establishing...

The role of non-criteria antibodies remains not well understood. One of the recent studies published on this topic provides helpful guidance. The study titled "Added value of antiphosphatidylserine/prothrombin antibodies in the workup of thrombotic antiphospholipid syndrome: Communication from the I...

There is notable positivity in these labs found in patients with pregnancy losses. Whether it is correlative or not is yet to be determined.