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Does PT/PTT elevation due to severe vitamin K deficiency protect against thrombosis?

2 Answers
Mednet Member
Mednet Member
Hematology · Medical University of South Carolina

Yes, most of us think that vitamin K deficiency increases the risk for bleeding rather than protecting against VTE.

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Mednet Member
Mednet Member
Hematology · Mayo Clinic

In theory, having a prolonged PT/APTT due to severe vitamin K deficiency should be protective against thrombosis. However, the etiology of being so severely vitamin K deficient needs to be addressed. In addition, this scenario is not a 'controlled' situation and the INR may fluctuate putting the pat...

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