Does PT/PTT elevation due to severe vitamin K deficiency protect against thrombosis?
2 Answers
Mednet Member
Hematology · Medical University of South Carolina
Yes, most of us think that vitamin K deficiency increases the risk for bleeding rather than protecting against VTE.
Mednet Member
Hematology · Mayo Clinic
In theory, having a prolonged PT/APTT due to severe vitamin K deficiency should be protective against thrombosis. However, the etiology of being so severely vitamin K deficient needs to be addressed. In addition, this scenario is not a 'controlled' situation and the INR may fluctuate putting the pat...