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Does the presence of thrombus in the sinus affect your decision between fractionated radiation and SRS for recurrent grade 1 meningioma?

Would extent of thrombus occlusion (non-occlusive versus fully occluded) change your recommendation?
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When treating a meningioma with radiation, does the tumor’s proximity to venous sinuses influence your choice of fractionation scheme?

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2 Answers
Mednet Member
Mednet MemberInvited Expert
Radiation Oncology · University of Arizona
Answered on

The presence of a thrombus in the venous sinuses can be a significant risk factor for post-treatment complications after SRS for meningiomas originating near or attached to the sinuses. Venous sinus thrombosis can be increased by the SRS, leading to venous infarction, which can cause a range of neur...

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Mednet Member
Mednet MemberInvited Expert
Radiation Oncology · GammaWest Cancer Services
Answered on · Updated on

This is a very interesting question and sheds light on important issues regarding symptomatic edema with meningioma. As Dr. @Dr. First Last points out nicely, venous sinus compression or invasion plays a role and must be considered. Another way to view the risks for symptomatic edema is to realize i...

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