For a patient otherwise suitable for APBI, would neoadjuvant endocrine therapy administered for extemporizing reasons (e.g., COVID diagnosis and recovery, rather than downstaging) preclude consideration of APBI?

Topics: Breast Cancer • Radiation Oncology

Answer from: Radiation Oncologist at Academic Institution

I have not typically treated patients with APBI if undergoing neoadjuvant therapy (chemotherapy or endocrine therapy). In theory, if endocrine therapy was a short amount of time, PBI could be considered but I have favored HWBI in these situations.

Comments

Radiation Oncologist at Washington University School of Medicine
I agree with @Chirag S. Shah (always a good option...

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