For an asymptomatic patient discovered during workup for elevated PT/PTT to have mild prothrombin deficiency, would you suggest any preoperative prophylaxis?
Level >60%. No family or surgical h/o of bleeding but heavy postpartum bleeding.
Answer from: at Community Practice
In someone with normal liver function otherwise, who was found on preoperative screening to have both mildly prolonged PT and PTT, AND the only abnormality found was a factor II (2, prothrombin) level >60%, I would not administer preoperative prophylaxis. However, I find the question confusing as...
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Answer from: at Community Practice
The generally accepted hemostatic level for prothrombin is 40%. It is doubtful that the 40% level is the cause of her past bleeding or a cause of the prolonged PT and PTT. I'm assuming that a mixing study showed a correction of the level and that her lupus anticoagulant is negative.
A bleeding as...