For an otherwise resectable esophageal cancer with involved celiac lymph nodes, would you ever consider an SIB beyond 50.4 Gy?

Intuitively, it seems like 50.4 Gy is not enough, as pathologic complete response rates are low.

Based on multiple randomized trials, no dose higher than 50.4 Gy has been superior to 50.4 Gy for esophageal cancer. This included the primary tumor and grossly involved nodes. The NCCN now recommends st...