For how long do you treat an early spinal hardware infection secondary to MSSA after operative washout and retention of hardware?

This infection is a key research interest of mine and one I'm deeply passionate about. I typically treat with a 12-week induction regimen, preferably using antibiofilm-active agents—an approach adapted from the DATIPO trial for prosthetic joint infections (PJI). I generally do not recommend routine ...

Tricky issue. I typically will treat for 6 weeks (a few days IV and quick transition to PO). Then, after 6 weeks, I watch for recurrence. If that happens, I suppress for... time? Can consider using rifampin combo Rx though I am not sure if there is a final answer on that question. There was an excel...

I don't think there are a lot of great data on this topic. In theory, it would seem to resemble a PJI that undergoes a DAIR procedure, although the differences in tissue blood flow/etc, might not make them entirely similar. But given no great data, I lean toward 12 weeks per DAIR in DATIPO to start ...