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Topics:
Immune-related adverse events • Rheumatology • Rheumatoid Arthritis • Spondyloarthritis • Immune Checkpoint Inhibitor
For ICI arthritis, how soon do you start DMARDs?
Answer from: at Academic Institution
Great question! This is complicated- is it one joint? Inject with steroids! Are there many joints? Is it gout-based, spondyloarthropathy, or more like seronegative RA or PMR-like?Also, where are they in the cancer space? In surveillance but high risk, what type of cancer, etc, etcI start this w...
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Answer from: at Academic Institution
This is a loaded question: If you are a rheuamtologist the answer is always at the same time, the entire goal to get off steroids. Steroids are your best friend and worst enemy, meaning: the most reliable and quick, cheap way to decrease inflammation -- this is the bridge to by time until of the dru...
Answer from: at Community Practice
Keeping in mind that oral steroids can decrease the effectiveness of immunotherapy, therefore if need for chronic steroids, then there is need for a DMARD! Remember to discuss with oncology and have the pharmacist confirm that there are no interactions with current cancer regimen and DMARD of choice...