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For newly diagnosed BRAF mutated melanoma with brain metastases, do you prefer to start with targeted therapy or with immunotherapy?

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What is the preferred systemic therapy option in BRAF mutated metastatic melanoma in the brain?

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1 Answer
Mednet Member
Mednet MemberInvited Expert
Medical Oncology · University of Texas MD Anderson Cancer Center
Answered on

Selection of systemic therapy, targeted therapy versus checkpoint immunotherapy, relies upon a comprehensive evaluation of patient's performance status, the number, size and location of brain metastases (BMs), neurological symptoms, and the extent of extracranial disease.

1. If the patient has poor ...

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