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For patients with candida species osteomyelitis who have undergone extensive surgical debridement, do you routinely still recommend 6-12 months of antifungal therapy or opt for a shorter duration?

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Do you routinely recommend 6-12 months of antifungal therapy for patients with Candida species osteomyelitis who have undergone extensive surgical debridement, or do you consider a shorter duration based on clinical response and patient-specific factors?

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1 Answer
Mednet Member
Mednet Member
Infectious Disease · University of Arkansas for Medical Sciences College of Medicine
Answered on

After removal of hardware, if present, and debridement of infected bone, my practice is to treat Candida osteomyelitis with an intravenous echinocandin for two weeks followed an oral azole, to which the fungus is susceptible, for at least six months. If full debridement is not possible, such as vert...

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