For patients with seminoma testicular cancer who are Stage II (positive retroperitoneal lymph nodes), what factors do you consider when choosing between radiation versus chemotherapy?

I usually look at the size of the retroperitoneal adenopathy, the age of the patient and the anticipated tolerance of chemotherapy. Disease > 3cm in the retroperitoneum is most often treated with chemotherapy. Less than 3 cm, it becomes a clinical judgement. Older patients probably have lower risk o...