For patients with spinal hardware infections, in what circumstances do you recommend 12 weeks over 6 weeks of antimicrobial therapy?

Extrapolating from PJI data, I tend to treat longer, but not always IV if there is an oral option after initial IV therapy.

A big blurry line is when do oral antibiotics stop being for treatment and start being suppressive?

Anyone I'm considering for long term suppressive antibiotics, really gets a longer course. If they respond well (reduction in pain, normalization of inflammatory biomarkers), I can transition them to pills, understanding that they will be on pills for a long time (12 months t...