For patients with stage I NSCLC initially treated with SBRT, how do you best manage isolated regional nodal failure?

The 5-year loco-regional failure rate in RTOG 0236 was 38%, underscoring that there is considerable need for identifying a post-SBRT salvage strategy for these patients; there are only anecdotal reports in the literature as to how to best manage these patients. Our historic approach when the failure...

There is limited prospective data to guide us on the answer. Our group did write up and get published our experience with this very question a few years ago. The basic take-home message was that in our experience these patients clinically behave like the updated stage they have at progression. We wo...

...This is a very important clinical question, especially as more and more patients are having SABR/SBRT to treat their early-stage lung cancer.

Invariably, we will see more isolated local/regional recurrences that will require treatment.

However, there has been limited data guiding us on how to rescu...