For which patients with type 2 diabetes mellitus would you consider switching to once-weekly basal insulin (Awiqli)?

Once weekly basal insulin is an advance in diabetes pharmacology, but it will not be optimal for everyone. I would suggest it for people with a very stable eating and activity schedule week to week, and may have problems with adherence to or reluctance to daily basal insulin. This may work well for ...

I have no experience with weekly basal insulin. If well-controlled with daily basal insulin, no reason to switch. Probably the best use would be for patients reluctant to start insulin.

There isn't a clear "best" patient profile for once-weekly basal insulin. Having said that, the following are potentially characteristics to consider as appropriate for once-weekly insulin:

• Poorly adherent daily insulin user
• Older adult with cognitive or physical limitations
• Patients with comorbidi...

Patients unable to take insulin daily due to cognitive impairment. I would aim for fasting glucose of 150, not 120.