Given the new ASCO guidelines on SNB in early stage breast cancer, how does the omission of SNB in patients aged 50-70 impact your adjuvant radiation recommendations?

If the patient is otherwise a good candidate for APBI (age > 50, pT1 tumor, ER+, HER2 negative, Recurrence score low and intending to take endocrine therapy) that was clinically node negative and ultrasound axilla negative, I feel completely comfortable treating with APBI post lumpectomy with negati...

Based on the EBCTCG RNI meta-analysis, DBCG, and MA.20, I would consider RNI in patients with central or medial tumors or those with T2 grade 3 disease.

However, I've encouraged our surgeons to continue SLND, at least in patients aged 50-70.

What should the primary outcomes be in INSEMA and SOUND? I...