Has the FROSTBITE-2 trial changed how you choose between cryoprobe and forceps for transbronchial biopsy in your practice?

FROSTBITE - 2 trial suggested that cryobiopsy was associated with a high diagnostic yield and a satisfactory safety profile. Overall, cryobiopsy using the 1.1 mm cryoprobe for nodules, ILD, and post-transplant biopsy would be my first choice.

The data from FROSTBITE-2 is compelling. Every case is different and need its singular approach but there seems to be a benefit on using cryobiopsy for lung biopsies, especially in the work up of lung nodules and for interstitial lung disease. An important aspect to take into account is the economic...