Have you had patients who wish to take ivermectin and/or fenbendazole as adjunct treatments for gynecologic cancers, and if so, how have you handled this?

Since COVID, there are definitely more patients interested in ivermectin and/or fenbendazole, as well as other alternative therapies. I will counsel the patients on the data for standard of care therapy, but also acknowledge that it is also their body, their life, and ultimately their choice what treatment they opt to pursue. I explain that based on the data, I will not prescribe these treatments, but that if they have access to and choose to use any alternative therapies, I just want to make su...

I have a number of patients asking about these alternative regimens for their cancer treatment, not meaning to be adjuvant but also as main treatment strategies, in lung cancer (not Gyn Onc). The social media recent postings, especially from some celebrities claiming cancer remission in friends with distant stage 4 metastatic disease in remission, cancer-free after taking these regimens, pose great challenges for us to address the question with our patients.

I have a metastatic SCLC patient in E...

I agree with Dr. @Dr. First Last answer wholeheartedly. I typically inform them of the lack of data and concerns for the safety of these therapies for the treatment of gynecologic cancers. I often direct patients to the recently published review in Gynecologic Oncology Reports: Mujumdar et al., PMID 40851910. If they are interested, I print a copy of the paper to help inform them of the scientific rationale for why I recommend against the use of ivermectin.