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Have you used Karius to aid in the diagnosis of a non-resolving pneumonia, with negative bronchoscopy, biopsy, and other infectious work up in an immunocompetent patient?

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Do you routinely use Karius to aid a diagnosis of non-resolving pneumonia in immunocompetent patients who have had a negative broncoscopy?

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1 Answer
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Infectious Disease · University of Louisville Health Sciences Center
Answered on

Culture-negative hospital-acquired pneumonia is approximately 50%. Positive cultures are complicated by having to correlate results clinically as organisms may contaminate specimens (even if from a protected brush) and include an organism that doesn't even cause pneumonia, such as Enterococcus spp. ...

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