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How do you adjust transplant-benefit–based decision-making for HCC patients with prior immune checkpoint inhibitor exposure, given the potential for increased peri-transplant rejection or graft loss?

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At your institution, at what time-frame does your transplant program pursue liver transplant after the last dose of ICI?

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1 Answer
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Mednet MemberInvited Expert
Hepatology · Mount Sinai Hospital
Answered on

Some programs aim not to proceed with transplantation (LT) for 1 month subsequent to the administration of immunotherapy in order to avoid rejection. However, this is not often feasible, and the reality is that the half-life of these medications can be closer to 50-60 days. My personal opinion is th...

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