How do you approach a thoracic lymph node that is highly suspicious on CT and PET but negative on EBUS in patients with NSCLC?

Our institution is very privileged in having a very large, highly expert team of interventional pulmonologists. In the cases where we are conflicted over how to interpret imaging of concerning lymph nodes, and where we have had the chance for a deep dive at tumor board and accompanying expert radiol...

I agree with Dr. @Dr. First Last in the setting of a highly expert interventional pulmonology (and pathology) team.

However, there can be a large range of diagnostic yield and false negative rates depending on expertise and technique. Some factors help distinguish a "negative" biopsy from a "non-dia...

Briefly, a lymph node that is highly suspicious on CT and PET but negative on EBUS in patients with NSCLC, EBUS is performed by experienced interventional pulmonologists with ROSE to confirm adequacy and discussion with cytologist should be discussed in a multidisciplinary fashion and likely referre...