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How do you approach ADT and pelvic lymph node radiation in the salvage setting for patients with a PSA <0.5 ng/mL?

How do the results of RTOG 0534 presented at ASTRO affect your decision making?
2 Answers
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Radiation Oncology · Case Western Reserve University/ University Hospitals Seidman Cancer Center
Answered on

This is an important and timely question.

As I have previously written on this forum, I highly recommend those interested in first reading https://www.ncbi.nlm.nih.gov/pubmed/30238901, which outlines those who should and shouldnt receive ADT with salvage RT. In general, those with PSA <0.5 should rec...

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Radiation Oncology · Varian Medical Systems/Allegheny health network
Answered on

Axumin and PSMA scan will redefine how we treat in salvage setting. Lower salvage rate with higher PSA in previous studies could have been because we were treating the wrong target (prostatic bed) vs. recurrent nodal disease which were not picked up by conventional scan (Higher sensitivity of these ...

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