How do you approach dosing of anakinra in MAS?

Topics: Pediatric Oncology • Rheumatology • Hematology • Pediatric Hematology • General Rheumatology • HLH • Pediatric Rheumatology • Multispecialty Spotlight

Answer from: at Community Practice

We generally start with dosing per the rheumatology guidelines of 100 mg/day (1-2 mg/kg in children) subcutaneously. Based on case reports, if this is insufficient to control the hyperinflammation, can be increased (see Ajeganova et al., PMID 33281955).

Comments

at Kaiser Permanente
Do you have guidelines on IV dosing? Thank yo...

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