How do you approach maintenance therapy for relapsed follicular lymphoma?

Topics: Hematologic Malignancies • Medical Oncology • Lymphoma • Hematology

Specifically, do you consider repeating maintenance therapy after second line therapy if a patient had already received 2 years of maintenance rituximab with frontline therapy? Does it matter if the relapse is > 12 months or < 12 months after frontline therapy?

Answer from: Medical Oncologist at Community Practice

In general, patients who received 2 years of maintenance rituximab in first-line settings are unlikely to benefit from more maintenance rituximab in second-line. This is especially true if relapse occurs within 24 months of first-line therapy.A meta-analysis (JNCI 2011) did show a small benefit in o...

Comments

Medical Oncologist at Berkshire Hem Onc PC
What about maintenance obinutuzumab as an alternat...

Medical Oncologist at Mayo Clinic College of Medicine and Science (Scottsdale)
Data for obinutuzumab comes from GADOLIN. In patie...

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