I consider TM or longitudinal myelitis an emergency. I have been pretty aggressive in my treatment with this diagnosis, and have treated a case with pulse steroids, plex, and Cytoxan with excellent outcomes. The main challenge in such situations is differentiating overlapping MS or other autoimmune ...

In treating transverse myelitis, early aggressive interventions can decrease the long-term neurologic morbidity. If a patient has significant neurologic symptoms, I typically manage with both 5 days of IV methylprednisolone and plasmapheresis. I also perform brain MRI (to evaluate for demyelinating ...