How do you approach managing depression symptoms in patients who have had repeated high risk of bleeding?
When do you determine SSRI therapy is unsafe to pursue in such situations?
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Do you avoid using SSRIs in patients with high bleeding risk?
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2 Answers
Mednet MemberInvited Expert
Psychiatry · University of Colorado
Answered on · Updated on
Overall, evidence suggests that while SSRIs do increase the risk of bleeding. The absolute risk of a bleeding event remains low and is usually not serious. A 2017 meta-analysis by Laporte et al., suggested that overall bleeding risk is increased by at least 36% while other meta-analyses suggest that...
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Mednet Member
Psychiatry · Private Practice
Answered on
Use vitamin C 500 mg TID. If minimal response, add vitamin K2 to the regimen to reduce the risks.
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