How do you approach pathologic review and genomic testing, if indicated, of a spindle cell neoplasm?

Experienced sarcoma pathologists should review cases such as this. The rate of a change in diagnosis upon pathology review at a sarcoma center, after an initial review by a general pathologist, is surprisingly high (Ray-Coquard et al 2012, Annals Oncol).

Unless there is a specific diagnostic concern...