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How do you approach repeat SBRT in the abdomen, specifically when considering constraints for bowel and mesenteric vessels?

Assume that a patient has had >1 year since previous SBRT treatment, and that they are not a surgical candidate. The previous dose was 30 Gy in 5 fractions for a metastatic colon cancer. Would you ever constrain the mesenteric vessels similarly to the great vessels in thoracic SBRT?
3 Answers
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Radiation Oncology · Massachusetts General Hospital
Answered on

Great question with no clear guidelines. If it was the same lesion of prior RT, I would consider other liver-directed therapies as I would worry about the ability to get in meaningful dose. If it was a different lesion, I would create a cumulative plan and try to minimize bowel dose aggressively. If...

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Radiation Oncology · Fox Chase Cancer Center
Answered on

I generally agree with Drs. @Dr. First Last and @Dr. First Last. I do not constrain the dose to mesenteric vessels. The dose is limited by the luminal GI structures such that the vessels should not be at risk.

In the case of a patient who was treated over a year ago, we would typically create a plan ...

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Radiation Oncology · Sunnybrook Health Sciences Centre
Answered on

Perhaps a little bit more information would be helpful. What was previously treated - liver? Or mesenteric metastatic node? Or PA/RP node? For liver, 30/5 seems low.

If it was mesenteric mass/node repeating radiation to the same lesion may not be beneficial, in my opinion. The dose you would be able...

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