How do you approach selecting optimal muscle biopsy site when evaluating a patient for suspected inflammatory myopathy?

There are a few things to consider when formulating your approach to this, which include 1) the clinical exam, 2) ease of biopsy of muscle, and 3) potential confounders of diagnosis.

The goal is to get a specimen from a muscle that is undergoing active inflammation. These muscles will generally be w...

EMG or MRI.