How do you approach the adjuvant treatment of glioblastoma following up-front laser interstitial thermal therapy (LITT)?

This is an emerging area with very limited information; there are no large prospective trials to adequately answer the question. The issues faced by a Radiation Oncologist include:

1. Interpretation of the post-op scan: what is the true GTV? This remains unclear; we include all enhancing abnormality...