How do you approach the initial dosing of carfilzomib for patients with relapsed multiple myeloma?
Is the therapeutic purpose of the proteasome inhibitor to maximize total dosage per week or number of infusions per week?
Community PollStarted
How do you dose carfilzomib for relapsed multiple myeloma?
Join Mednetto vote and see how they answered.
2 Answers
Mednet MemberInvited Expert
Medical Oncology · University of Chicago
Answered on
A great question and one without a uniform answer!
I place a lot of focus on patient quality of life, and one of the recurring themes from patients is the number of visits to the medical center. A twice-weekly regimen of carfilzomib (or bortezomib for that matter), over the course of a year, results...
Join for free or sign in to see the full answer
Mednet MemberInvited Expert
Medical Oncology · University of Washington, Fred Hutchinson Cancer Research Center
Answered on
Could not agree more with Dr. @Dr. First Last. "Home time" is tremendously important to our patients, and the efficacy bar to default to twice-weekly carfilzomib should be quite high to justify its use. As two quick additions to his expert comments:
- We will someday have an answer about twice-weekly ...
Join for free or sign in to see the full answer