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How do you approach the management of extremely low LDL levels in older adult patients receiving statin therapy for primary prevention of cardiovascular disease?

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How do you approach the management of extremely low LDL levels (e.g., <20) in older adult patients receiving statin therapy for primary prevention of cardiovascular disease (and no myalgias/musculoskeletal complaints)??

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1 Answer
Mednet Member
Mednet MemberInvited Expert
Cardiology · Washington University School of Medicine
Answered on

In the absence of side effects, I am not concerned about very low LDL levels (e.g., less than 20 mg/dL), as there is a fairly linear association between LDL and CV risk, and there is no convincing evidence that even extremely low LDL levels are associated with cognitive impairment, intracranial hemo...

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