How do you approach the use of fidaxomicin versus vancomycin for initial Clostridioides difficile infection in immunocompromised patients, considering the lower recurrence rates but higher cost of fidaxomicin?
Atamna et al., PMID 41439186
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Are you able to routinely prescribe fidaxomicin, or do you still primarily use vancomycin due to high cost and inadequate insurance coverage in your practice setting?
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Infectious Disease · Stanford
Answered on
Whether immunocompromised or not, fidaxomicin has been demonstrated to be superior to vancomycin – not in resolution of the acute infection but in reducing the risk or recurrence by approximately one-half. In one study of hospitalized patients published in 2015, it was reported that, when taking int...
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