How do you approach the use of metformin in the management of prediabetes for patients who are neither obese nor have a family history of diabetes?

When considering the approach to a patient with a diagnosis of pre-diabetes, I think it is important to be sure the patient actually meets criteria. Most of us screen patients at risk with A1C levels because it is so much easier. However, A1C levels do not fully correspond to glucose levels and may ...

Metformin is not approved by the FDA for use in prediabetes. NO drug is approved for the treatment of Prediabetes. Thus, their use would be considered off-label. However, the American diabetes association states that the use of Metformin can be considered in subjects with a BMI of 35 or more, patien...