Topics:
Radiation Oncology • Neuro-Oncology
How do you approach treatment of an unresectable sacral chordoma?
What would be your preferred treatment technique and dose/fractionation?
Answer from: Radiation Oncologist at Academic Institution
Definitive RT, preferably with protons.
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Answer from: Radiation Oncologist at Academic Institution
Agree. Definitive RT with protons.
79.2 Gy (RBE) in 44 fractions to GTV.
50.4 Gy (RBE) in 28 fractions to CTV.
Comments
Radiation Oncologist at Mallory Radiotherapy, PLLC
What margins do you use?
What margins do you use?
Answer from: Radiation Oncologist at Academic Institution
As stated, definitive-intent RT. Evidence is strongest for protons, though SBRT is also a consideration. The available data are reviewed here: Konieczkowski et al., 32147017.Outcomes for unresected chordomas are actually quite promising when treated at experienced centers—e.g., Kabol...