How do you approach very treatment-refractory ITP?

Topics: Pediatric Oncology • Medical Oncology • Thrombocytopenia • Hematology • Pediatric Hematology • Benign Hematology • ITP

Such as the case in which a patient is unresponsive to steroids, IVIG, TPO-agonist, rituximab, splenectomy, and even fostamitinib.

Answer from: at Community Practice

Severely refractory ITP doesn't account for a large fraction of ITP patients, but it can be quite a challenge for treaters and patients alike. Combination therapies, varied immunosuppressive agents, and careful checks on adherence are all helpful. Some alternative agents with entirely different mech...

Comments

at Harvard Medical School
A beautiful and well-considered answer. In additio...

Related Questions