How do you choose roflumilast vs ensifentrine in COPD patients with dyspnea despite adequate LABA + LAMA (+ ICS therapy where indicated)?

Hi - I don't think there is a clear answer for this. However, in my practice I rarely use roflumilast for dyspnea (mostly for exacerbation prevention). I have been trying ensifentrine in some of these dyspneic COPD patients, in part because they are wanting to "try something new". So far, I have see...