How do you consider the clinical relevance of elevated serum B12 levels as a marker of underlying hepatic disease?
Should this finding in patients not taking B12 supplements prompt further investigation?
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Would an incidental elevated serum B12 level prompt you to pursue further workup of underlying hepatic, renal, and/or hematologic disease?
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1 Answer
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Hospital Medicine · UT Health San Antonio
Answered on
Elevated B12 levels have shown significant relevance and significance to many underlying conditions, particularly a high correlation with underlying liver disease. About 1 in 5 to 1 in 4 B12 levels >1000 pg/ml had a significant correlation. It is a prognosticator, in my opinion, and the literature s...
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