How do you consider the role of probiotics for mucositis mitigation in patients receiving head and neck radiotherapy?

This is a very interesting study and I am excited to see continued studies into symptom mitigation for definitive chemoRT.

I currently offer Ssk12 to my patients undergoing H+N RT (definitive or adjuvant). I see little potential downside as it is a relatively inexpensive intervention and they report minimal side effects in the study.

My one primary concern is the formulation. The specific brand used in the study is currently out of stock on Amazon (and elsewhere online) and while there are other brands available, I am somewhat skeptical of the QA/QC of the myriad of supplement brands on online retailers and if there are meaningful differences in the probiotic composition between brands.