How do you counsel a young woman carrying a BRCA 1 or 2 mutation and history of breast cancer who desires pregnancy?

Pregnancy subsequent to breast cancer does not worsen the prognosis. If a young BRCA carrier desires to become pregnant she should be supported. Points to emphasize: 1) the rates of ovarian cancer don't begin to rise until after 35 years; 2) she can be screened by breast ultrasound during pregnancy;...

Agree. Young women with known germline mutations in BRCA1/2 mutation can successfully go on to conceive after adequate treatment of their breast cancer without compromise of prognosis. Regardless of tumor subtype, the risk of recurrence is the highest in the first few years, if patients are on tamox...