How do you counsel patients on the use of berberine to prevent the progression of prediabetes to type 2 diabetes mellitus?

Berberine is a traditional Chinese medicine extracted from various plants. It has been reported to lower glucose, blood pressure, cholesterol, and weight, but the studies have varied greatly in quality. A recent meta-analysis (Liang et al., PMID 30393248) found a positive impact on glucose in patien...