How do you counsel patients regarding the improvement they can expect when starting nemolizumab?

I tell patients that this medicine is a relatively newly approved medication in dermatology, although we have had significant experience with it in veterinary medicine for years. I state that the benefits of this drug go beyond just improving itch and skin clearance, but also have a role in impactin...

I tell my patients that you can expect some improvement within 1-2 weeks and maybe sooner. However, I counsel they should give it at least 2-3 months before they decide the Rx did not work. The NRS itch score is helpful to quantify, but clinically meaningful in the real world is determined by how sa...

I agree with what has been said so far and would add that I recommend a longer trial of 6 months before categorizing as a treatment failure. A few of my most challenging PN cases have had excellent results but didn't see major improvements until month 4-6.