How do you counsel patients who prefer to continue TNFi therapy indefinitely for rheumatoid arthritis despite long-standing remission?

I explain the risk of stopping and having a return of disease after stopping (that this could be a “drug holiday” of limited duration) and that this return of disease activity may not respond to restarting the TNF blockade therapy that had been working well for them. Then they would have to start a ...

I wouldn't stop it especially if RF is still positive.

I agree with the cautious response outlined by Drs. @Dr. First Last & @Dr. First Last in the risk of a challenged RA flare with the withdrawal of iTNF therapy; I tend to for Boolean criteria-1 before having the discussion. I personally like to perform ultrasound on these patients, using Dr Naredo’s ...