Topics:
Gastrointestinal Cancers • Medical Oncology • Colorectal Cancer • NCI-CCC Tumor Board Question • Yale • NCI-CCC GI Tumor Board Question
How do you decide what induction chemotherapy regimen to use for a patient with locally advanced rectal cancer (cT4N1) receiving total neoadjuvant therapy?
Would you use FOLFIRINOX as in Prodige 23 or FOLFOX as in RAPIDO?
Answer from: Medical Oncologist at Academic Institution
The approach for a locally advanced rectal cancer (cT4N1) requires the consideration of many patient and cancer-specific factors. It is our practice that all new cases of rectal cancer undergo pelvic MRI including the use of rectal contrast to confirm staging with a dedicated assessment of nodal sta...
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