How do you decide when to extend rituximab redosing beyond a 6 month interval for replasing multiple sclerosis?
In light of the publication by Langer-Gould et al., PMID 41852088.
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What is the longest interval you will use for rituximab redosing in relapsing multiple sclerosis?
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2 Answers
Mednet MemberInvited Expert
Neurology · UTHealth
Answered on
In light of the published study, the discussion that I've had with patients revolves around utilizing CD19/CD20 counts to guide infusion frequency.
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Mednet MemberInvited Expert
Neurology · Cleveland Clinic
Answered on
I start discussing extending the dosing interval after the first year on rituximab, but rather than at set 12-month intervals, I also use B-cell repopulation (CD19 counts) as a guide.
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