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When would you obtain optic nerve testing in patients suspected to have multiple sclerosis without a clinical history of optic neuritis?
e.g. MRI orbits, optic coherence tomography (OCT), visual evoked potentials (VEP)
Answer from: at Community Practice
Occasionally, to pick up subclinical disease in making an early diagnosis, I will request pattern-shift VEP. Picking up a silent lesion can help with the "dissemination in space" criteria, now that the optic nerve is considered part of the topography for MS lesion location in the new diagnostic crit...
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Answer from: at Community Practice
A key change in the 2024 revision of the McDonald criteria is the addition of the optic nerve as a fifth anatomic location to demonstrate dissemination in space (DIS) in addition to periventricular, cortical/juxtacortical, infratentorial, and spinal cord, which were included in the 2017 criteria. Op...